Overview

RI-Biomics technology is a fusion technology by which radioactive tracer is synthesized, analyzed and evaluated in vivo kinetic property (adsorption, distribution, metabolism and excretion) and quantitative biological effect of drug or medicinal food. And it also covers a study on phenomena of life using radioisotopes. Recently radioisotope based biochip and kits were developed and also is extending to study on the radiotracers of biotechnology, agriculture, food and environment science.

Research objectives and contents

Taking the advantage of high sensitivity of radioisotope, a variety of fusion researches are performed
to study on the phenomena of life to contribute improving quality of life and healthy human being and environment.

For this, RI-Biomics center is carrying out research projects based on RI application technologies as below,

• Researches on effective labeling and synthesis methods for development of radioactive material

  • Development of radioactive tracers for the new medicinal material and drug candidate
  • Development of high efficacy carrier and remover of radioisotope
  • Development of radioactive tracers for harmful chemical substance to assess the bio-effects on the living system

• Researches on the evaluation of the phenomena of life using radioisotope application

  • Development of kinetics property (absorption, distribution, metabolism, excretion) evaluation methods using radioactive new drug and drug candidate tracers (RI-ADME)
  • Development of radioisotope based molecular imaging technology
  • Development of application technology for radioactive materials

Main achievement

• Expertises and experiences for the radiosynthesis and RI-ADME evaluation
• Technical export to Swiss MMV related to ¹³¹I-, ¹⁴C- labeled anti-malaria drug (Pyronaridine tetraphosphate)
• Designated as the Advanced Research Center for Nuclear Excellence by Ministry of Education and Science Technology (MEST) in 2012
• Development of biochip technology applying the radiation detection technology for rapid and quantitative detection
• Nanoparticles for the radioisotope carrier
• Highly effective devices and methods for the removal of radioiodine
• Evaluation of in vivo residual property of PHMG using ¹¹¹In-PHMG